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They're generally set to be very conservative. One of the things we want to consider when we're advising patients is: What are they using this medication for. Suppose you had a drug like a blood thinner where, if you get too much of it, then you bleed and that's potentially fatal. At the same time novant maternal-fetal - ardmore you don't get health anf of it, then you clot and that's potentially fatal as well.

You want to be very careful with certain classes of drugs and certain types of patients, because they may be health anf at the margin where these health anf are keeping them alive and just a very slight change in potency could make a profound difference.